https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27950 in vitro invasion assays showed that siRNA against KRT1 was able to reverse the DHA-induced inhibition of breast cancer cell invasion. In conclusion, KRT1 is involved in the anti-invasive activity of DHA in breast cancer cells.]]> Wed 11 Apr 2018 15:01:51 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45006 Thu 23 Mar 2023 13:24:35 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:7759 Sat 24 Mar 2018 08:41:54 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:17408 Sat 24 Mar 2018 08:01:37 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:18941 Sat 24 Mar 2018 07:58:59 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:25816 Sat 24 Mar 2018 07:34:38 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29529 Sat 24 Mar 2018 07:32:27 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:25886 Sat 24 Mar 2018 07:25:52 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:39180 n = 29/32) were included in the current analysis (male: n = 22, 36.07%). DHA-enriched fish oil supplementation increased total testosterone levels in males after adjusting for baseline levels, age and BMI. There was no treatment effect in females. Changes in testosterone levels in males were positively associated with changes to omega-3 PUFAs EPA and DHA and inversely correlated with omega-6 PUFA, arachidonic acid and dihomo-gamma-linolenic acid content in erythrocyte membranes, and was associated with beneficial changes to fasting insulin and HOMA-IR across the course of the study. DHA-enriched fish oil supplementation increases testosterone levels in overweight and obese men. Further research is warranted to substantiate these findings with a larger sample size and a longer follow-up period.]]> Mon 23 May 2022 16:16:26 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:39169 n = 38) or 2 g corn oil (CO) /day (control, n = 35) for 12 weeks in a double-blind randomised controlled trial. A fasting blood sample was collected at 0 and 12 weeks for assessment of IR, glucose and blood lipid profile. Sixty-eight participants completed the intervention. Compared with CO (n = 32), FO (n = 36) significantly reduced fasting insulin by -1.62 μIU/L (95%CI: -2.99, -0.26,) (p = 0.021) and HOMA-IR by -0.40 units (95%CI: -0.78, -0.02, p = 0.038). Higher insulin and HOMA-IR at baseline were associated with greater reductions in the FO group (p < 0.001). There was no interaction between sex and treatment for the change in insulin (p-interaction_{sex*treatment} = 0.816) or HOMA-IR (p-interaction_{sex*treatment} = 0.825). DHA-enriched FO reduces IR in adults with abdominal obesity, however, sex-dependent differences were not evident in this study.]]> Fri 20 May 2022 16:31:18 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:52486 Fri 13 Oct 2023 10:03:34 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:41765 Fri 12 Aug 2022 11:49:26 AEST ]]>